Honour Roll of Australia-Harvard Fellows

Seq.

No

Aust-Harvard

Fellow

Research

topic

Senior Aust.

Collaborator

Australian
institution

Mths
in Aust

2010

25/26

James Macklin PhD, Dir of Collections & Informatics, HU Herbaria

Paul J Morris PhD, Biodiv-ersity Informa-tics Manager, HU Herbaria

Advancing the International Plant Names Index (IPNI), an ongoing collaboration between HUÕs Herbaria and Aust National Herbarium in A.C.T. Macklin & Morris will continue their work in helping develop the IPNI and test and prototype available technologies. Also prepare a technical implementation proposal for consideration by the Harvard Kew Australia IPNI  mgt team.

Collaboration exists betw. ANU/CSIRO and Australian GovernmentÕs Dept of the Environment, Water, Heritage and Arts for the Austn. National Herbarium program of the Centre for Biodiversity Research Drs Greg Whit-bread & Jim Croft,  CSIRO/ANU

Australian National Herbarium, Centre for Biodiversity Research (CBR). Also ANU/ CSIRO

1

 

 

 

Reports/Papers-1
Reports/Papers-2

24

John Quack-enbush, PhD, Prof of Biostat-istics & Comp-utational Biol-ogy., Prof of Cancer Biology, Dana-Farber Cancer Institute, Prof of Comp-utational Biol-ogy and Bio-informatics, Department of Biostatistics, Harvard School of Public Health

Utilise Dr WellsÕ existing database of olfactory stem cells, induce them to differentiate into a predetermined variety of cells, then build predictive models to understand the transitions from one state to another. Analyse these systems to identify the core pathways and create models that include stochastic elements believed to have wide application in basic and translational research. Extend by incorporating ideas from theoretical quantum physics (contÕd Col 5)

Dr Christine Wells, National Centre for Adult Stem Cell Research and Eskitis Insititute for Cell and Molecular Therapies, Griffith University, Nathan (southern Brisbane), Queensland. Also Professors Emma Whitelaw (QIMR, Brisbane) and Louise Ryan (CSIRO, Sydney)

Griffith University at Nathan (southern Brisbane), Queensland.

 

(contÕd) Ņto model the way in which cells explore the collection of possible state space trajectories that [may] improve our ability to predict responses to cellular perturbationsÓ. Likely to result in 2 scientific and 2 methodology papers

3





Reports/Papers

23

Ali Khadem-hosseini PhD (MIT), Assist Prof. Dept. Med. at HMS; also Div. of Health Sciences & Technology (HST) at MIT, Assoc Bio-engineer at Brigham & WomenÕs Hospital.

Supervise and train DehghaniÕs research team in: 1) Engineering of micro-scale cardiac tissue constructs comprised of cell-laden hydro-gels with interpenetrating microvasculature.

(2) Engineer biological complexity within micro-fabricated cell-laden scaffolds After tissue fabrication, properties of the tissue constructs will be ana-lysed including biomechan-ical properties (contÕd Col 5)

Assoc Professor Fariba Dehghani, PhD (UNSW), Associate Dean of Postgraduate Coursework, Director of Postgraduate studies, School of Chemical and Bio-molecular  Engineering, University of Sydney

School of Chemical and Bio-molecular  Engineering, University of Sydney

 

(contÕd) of the tissue constructs at various times after formation. Aim is to develop long term coll-aboration between USyd and Harv/MIT, and underpin future substantial research grants. Papers in preparation

 

2   




   

Reports/Papers-1
Reports/Papers-2



22

Richard (Rick) L Stevens PhD, Professor, Dept. Med. at HMS;

Div. Rheum., Immunol., & Allergy, at Brigham & WomenÕs Hospital.

Krilis and Stevens recently discovered that MCs and their tryptase mediators play key roles in a mouse model of IBD. AIMS of proposed research project:1. To deduce at the molecular level how MC-restricted tryptases participate in mild to moderate inflammation of the colon using experimental mouse models (contÕd Col 5)

Steven A Krilis, MB BS UNSW, PhD Syd, FRACP, professor Dept of Medicine, UNSW and St George Clinical School, St George Hospital, long-standing partnership in research of more than  20 years

Uni of NSW and St. George Clinical School

 

(contÕd) 2. To examine the role of MC tryptases in the breakdown and repair of the intestinal epithelial layer 3. To determine biological significance of MCs and their tryptase mediators in intestinal fibrosis.

6




Reports/Papers-1
Reports/Papers-2




2009

21

Kavi Bhalla PhD. Research Scientist, Sch.  Public Health, Harvard Initiative for Global Heath,. (International initiative to develop a know-ledge mgt framework for road traffic injury metrics in devel countries

Two one- month visits, each resulting in academic publication: 1) reclassify deaths to ill-defined causes of death categories in death registration data. Identify the best method for attributing these deaths to a known cause or condition & examine which poorly specified categories are important 2) Application of Global Burden of Disease (GBD) methods developed

(contÕd Col 5)

Professor James Harrison, School of Medicine, Flinders University, SA. who directs the Research Centre for Injury Studies (RCIS) which operates the National Injury Surveillance Unit of the Aust. Inst of Health & Welfare.

Flinders University, SA

 

(contÕd) for handling multi-trauma to real world data from developing countries. Test with Dr Belinda Gabbe (Monash U) how well the proposed methods perform on real world data from developing countries.

2




Reports/Papers-1

20

Steven W Lockley, PhD, Div of Sleep Medicine, HMS, Assoc Neuro-scientist, Div of Sleep Med, Brigham & WomenÕs Hosp. and Hon Assoc Prof. Sch of Psych, Psych and Psych Med at Monash Uni

1) Teaching courses in Bach Behavioural Neuroscience and BSc. involving Drugs, Brain and Altered Awareness and ŅIntegrative Neuro-scienceÓ. Also lecture series to Hons and PG students in Sleep & Chronobiology Research Program, incl weekly tutorials. 2) Contribute to Monash projects: Characterising sleep and circadian rhythm disruption in the blind, short

(contÕd Col 5)

Shantha M W Rajaratnam, PhD, Sen Lect, Monash Uni Co-investigator of study assessing relationship between Circadian amplitude and neuroticism with Dr Greg Murray of Swinburne Inst of Techn.

Monash Uni  and Swinburne Uni of Technology

 

(contÕd) wavelength sensitivity of the human circadian pace-maker, effects of extended work hours on sleep, alertness & performance of medical interns incl. work with Prof Grunstein (USyd) and Australasian Sleep Trials Network. 2) Supervise PhD students

2





Reports/Papers-1

19

Robert D Moir A/ Prof  and Instructor in Neurology HMS,  also Mass.General, Hosp, Boston

Develop synergies between Mental Health Research Institute & Harvard Med School.  Allow a big push on difficult collaborative projects in drug development for Alzheimer's and fertilise additional research by knowledge-exchange

Ashley Bush, Prof. of Pathology, Uni of Melb. pioneering researcher in AlzheimerÕs under Federation Fellowship at MHRI with Prof Colin Masters

Mental Health Research Institute, Univ of Melbourne

2



Reports/Papers-1

18

Harald Jueppner, M.D., Professor of Paediatrics, HMS, Head of Renal & Endocrine lab Unit, Mass General Hosp.

Continue existing collab. research on renal diseases caused by different underlying genetic diseases in a number of NSW families with known but undiagnosed genetic disorders. The Centre for Kidney Research at CHW at  USyd has been identifying unique Australian families with disorders affecting kidney development and/or the handling of minerals by the kidney.  (contÕd Col 5)

Dr Stephen Alexander, MPH (Harvard), Head of Kidney Research, Westmead ChildrenÕs Hosp. Studied under Jueppner, worked in MGH lab for 2 years

Westmead ChildrenÕs Hosp. & Uni of Sydney

 

(contÕd) Molecular analysis of these pedigrees may potentially allow the discovery of new genes with relevance not only to these families but also in our understanding of biology and disease.

1




Reports/Papers-1

17

Andrew P McMahon, Frank B Baird Prof of Science, (FAS), Dept of Molecular & CellÕr Biology, Harvard Stem Cell Institute, (Dept of Stem Cell & Regenerative Biology)

Two weeks at each of four  research & education centres (Syd, Melb, Bris, Adelaide) to give a series of lectures about Harvard research and broadly in developmental & regenerative biology in basic and biomedical research. Engage Australian scientists to discuss potential collaborative programs with HSCI / DSCRB. Forge research ties with Aust institutions and universities. 

Dr Patrick Tam, Dep Dir of ChildrenÕs Medical Research Institute, Sydney, and Profs. Peter Koopman & Melissa Little at Uni of Qld. Little is member of his Genitourinary Molecular Anatomy Project, a NIH-funded research co-op with strong Aust. component

ChildrenÕs Medical Research Institute, Univ of Sydney

2





Reports/Papers-1

2008

16

Simon Warfield PhD, Assoc Prof of Radiology, ChildrenÕs Hospital, Boston, Harvard Medical School.

To develop and stimulate imaging research of AlzheimerÕs disease & create a from collaboration between US-based Alzh. Disease Neuroimaging Initiative and CSIROÕs Australian Imaging Biomarkers & Lifestyle (AIBL) Flagship Study of Ageing. Enable early diagnosis.1) Optimise US MRI acquisition protocol for Aust purpose. 2) Apply quantitative image segmentation, to detect structural brain changes

(ContÕd Col 5)

Warfield is Australian. His BS, BE and PhD all granted at UNSW. This collaboration with CSIRO & Qld State Govt. at eHealth Research Centre, Brisbane, also Sydney and Melbourne

 

CSIRO & Qld State Govt. at eHealth Research Centre, Brisbane, also Sydney and Melbourne

 

(contÕd) 3) Multimodal unbiased statistical atlas to identify patterns of brain change

4) Lectures to grads and u/grads on latest imaging and analysis algorithms

3





Reports/Papers-1

15

Louise Ryan PhD, Henry Pickering Walcott Professor and Chair of Biostatistics at Harvard School of Public Health

1) Undertake research on spatio-temporal modelling and monitoring with applications in Health and Water Quality

2) Be a keynote speaker in a workshop on spatio temporal modelling organised jointly by Macquarie Uni, Uni of Wollongong and CSIRO

Dr Murray Cameron, of CSIRO Mathematical and Information Sciences. Also Dr Yougan Wang at CSIRO Brisbane.

Ryan herself is Australian.

CSIRO Mathematical and Information Sciences

3




Reports/Papers-1

14

Christopher French MBBS PhD, Neurology Fellow, Royal Melbourne Hosp, Research Fellow, Physiology Dept, Uni of Melbourne

Collaborate with Prof Kevin Staley, Div of Child Neurology, Mass. Gen.Hosp

1) investigate mechanisms of seizure cessation; 2) enlarge repertoire in synaptic transmission re epilepto-genesis; 3) bring techniques back to RMH/Uni of Melb for OÕBrien Group; 4) form research association between RMH & MGH / Harvard

Professor David Williams, Physiology Dept. Uni of Melb, also Professor Kevin Staley, HMS

Royal Melbourne Hospital, Univ of Melbourne

1.8





Reports/Papers-1

13

Felipe Fregni, Ass Prof, dir. of Clinical Trials Network at Beth Israel Medical Center, HMS

Pilot study using tDCS on savant-like cognitive skills to evaluate literal v. conceptual skills such as proofreading and change blindness. 10 healthy volunteers. Data collection and analysis

Professor Alan Snyder, dir Centre of the Mind, Uni of Sydney

Centre of the Mind, Univ of Sydney

0.6


Reports/Papers-1

12

Matthew W Gillman, A/Prof  Dept of Ambulatory Care & Prevention, HMS, Dept of Nutrition, HSPH

Work with Uni of AdelaideÕs ŅResearch Centre for the Early Life Origins of Adult Disease and Maternal Perinatal Clinical Trials UnitÓ to explore effects of interventions during pregnancy on childhood obesity and asthma.

Prof. Julie Anne Owens Head of School, Paediatrics and Reproductive Health, Discipline of Obstetrics and Gynaecology, Faculty of Health Sciences

Paediatrics and Reproductive Health, Univ of Adelaide

3



Reports/Papers-1

11

Ofer Levy MD PhD, Assistant Prof. Princ. Investigator, Dept of Medicine, Div of Infectious Diseases, ChildrenÕs Hosp Boston

Foster Ņcutting edge technical advancement eg genomic micro-array, multi analyte fluorometrics, etc. Collaborative report writing to expand a project in Australia studying Ņmaturation of neonatal responses to common bacterial pathogens

Close collaboration with Drs David Burgner, Tobias Strunk & Peter Richmond at Princess Margaret Hosp, Perth, and UWA. Burgner and Strunkl had worked in LevyÕs Boston lab recently.

Princess Margaret ChildrenÕs Hosp, Perth, and UWA

1.5




Reports/Papers-1

10

Paul F Hoffman, Sturgis Hooper Professor of Geology, Dept of Earth & Planetary Sciences, H.U.

Visiting Fellow at School of Earth & Environmental Sciences. U of A. Field work in S. Aust to test the Snowball Earth hypothesis. Also at Curtin Uni with paleomagnetist Dr Li to co-author a paper and give lectures at Curtin and UWA.

Dr Galen Halverson, Dept of Geology & Geophysics, Faculty of Earth and Environmental Sciences.

Faculty of Earth and Environmental Sciences. Uni of Adelaide

3



Reports/Papers-1

2007

9

Michael N Starnbach, A/Prof  Dept of Microbiology & Molecular Genetics, HMS. Fellow of the Academy at HMS

Integrate ongoing researches at HMS and QUT aimed at designing vaccines against Chlamydia trachomatis. StarnbachÕs lab has developed ŅT cell retrogenic (TCRrg) miceÓ that enables them to harvest Chlamydia-specific T cells and track them during infection

Profs Peter Timms and Ken Beagley, QUT Institute for Medical Research

Institute for Medical Research, Queensland University of Technology, Brisbane

2



Reports/Papers-1

8

Eric Mazur, Gordon McKay Prof of Physics & Applied Physics, Div  Engineering & Applied Sciences

Innovative physics education. Lectures, workshops, reviewing faculty practices, and research support on MazurÕs optics and ultra-fast lasers

Dr Anna N Wilson

Dept of Nuclear Physics and Dept of Physics, ANU

Depts of Nuclear Physics and Physics. Australian National University, Canberra.

1


Reports/Papers-1

7

Abraham Loeb, Prof of Astronomy, Harvard Uni

Ongoing collaboration since 2001 with Uni of Melb. linking with Harvard in the field of Ņfirst galaxiesÓ. Theoretical research supporting new Low-Frequency Dem-onstrator Project in West Australia.

Dr Stuart B Wyithe, Dept of Astronomy, Uni of Melbourne. Also visit Uni of Sydney

Dept of Astronomy, Univ of  Melbourne

3



Reports/Papers-1

2005 Š 2006

6

John Ayanian A/Prof Medicine, Health Care Policy, HMS; Dir, Gen. Med. Brigham & WomenÕs Hos

Comparative research on access to renal transplant and on chronic kidney disease outcomes by race  and socio-economic posi-tion in Australia and USA. Similar for lung, breast, prostate cancers et al

Dr Allan Cass, Dir Policy & Practice Div and Dir Renal Program, George Institute of Inter-national Health

George Institute of International Health, Royal Prince Alfred Hospital, Univ of Sydney

3

Reports/Papers-1

5

Sven-Erik Bursell, A/Prof Dept of Opthalmology HMS, Dir of JoslinDiabetes Center, Boston

Methods for detection of vascular damage and early treatment of diabetes including in indigenous and remote communities

A/Prof Alicia Jenkins, Dept of Medicine, St VincentÕs Hospital

Univ of Melbourne

3

Reports/Papers-1

4

Richard B Freeman, Prof of Eco-nomics, FAS. Dir Labor Studies NBER

Measure and determine economic consequences, policy implications of movements of engineers & scientists between Aust. UK,USA using NBER and Aust databases

Dr Max Tani, Sen Lecturer and Res. Fellow, UNSW at ADFA, Canberra

UNSW@ADFA (School of Business)

1.5

Reports/Papers-1

2004 Š 2005

3

Scott V Edwards
Prof of Organ-
ismic &Evolu-
tionary Biol.

Comparative genomics of
non-avian reptiles advance understanding of diversifn of chromosome & genomic structures in vertebrates

Prof Jenny Graves

Head of Genomics

Research Group,

Research School of Biological Sciences, ANU

3

Reports/Papers-1


2

Ashley Bush, A/Prof
of Psychiatry, HMS & Mass. General

AlzheimerÕs disease: zinc metabolism studies leading potentially to clinical tests for human abnormality and related diagnostic testing.

Prof Colin Masters, Director of Research, Head of Neurosciences,
Victoria

Mental Health Research Institute, Parkville, Univ of Melbourne

Vic.

3

Reports/Papers-1

1

CharlesBerul
A/Prof of Pediatrics

HMS & Boston

ChildrenÕs

Set up & train lab. staff
in mouse model prep

for heart electro-

physiology studies

Dr Diane Fatkin
Sr Bernice Res

Program in Heart

Disease

Victor Chang
Cardiac Res
Institute, Darlinghurst, Univ of NSW

0.5

Reports/Papers-1